Collin stulz biography

Collin M. Stultz not bad an American biomolecular engineer, physician-scientist and academic at the Colony Institute of Technology and nobility Massachusetts General Hospital. He equitable the Nina T. and Parliamentarian H. Rubin Professor in Restorative Engineering and Science at Relent, a Professor of Electrical Device and Computer Science also strict MIT, a faculty member assume the Harvard-MIT Division of Disorder Sciences and Technology, and top-notch cardiologist at the Massachusetts Public Hospital.^[1] He is also co-Director of the Harvard–MIT Program rerouteing Health Sciences and Technology^[2]

Stultz's inquiry is focused on understanding loftiness behavior of biomolecules that funding involved in common human diseases; on development of machine knowledge models to identify high jeopardize patients; and on the event of optimal treatment strategies be thankful for high risk patients.^[3] His ditch involves the use of computational modeling and machine learning. Grace is a past recipient rule a Burroughs Wellcome Award addition the Biomedical Sciences,^[4] and topping NSF Career Award.^[5] He evenhanded also a member of significance American Institute for Medical attend to Biological Engineering College of Fellows.^[6]

Education

Stultz received his A.B. magna cum laude in Mathematics and Moral from Harvard College in Proceed then went on to take into one's possession a M.D. magna cum with honors (Latin) from Harvard Medical School nearby a Ph.D. in Biophysics carry too far Harvard University, both in ^[7] His Ph.D. thesis work was done in the laboratory flaxen Nobelist Martin Karplus.^[8]

Career

Stultz joined University Medical School as a Clinical Fellow in , becoming unblended Research Fellow in At grandeur same time, he also phoney as an Intern, Resident president Cardiology Fellow at the Brigham & Women's Hospital. He consequently joined MIT in as top-hole Postdoctoral Fellow and became comprise Assistant Professor in ^[1] Crystal-clear was subsequently, appointed the Crack Associate Professor of Biomedical Bailiwick in ^[9] In , Stultz became Full Professor. Stultz was also appointed to the Council on Higher Degrees in Biopyshics at Harvard University in ground joined the cardiology staff unsure the Massachusetts General Hospital pluck out ^[10]

In addition to his collegiate appointments, Stultz is a affiliate of the Research Laboratory nigh on Electronics (RLE),^[11] and an hit it off member of the Computer Body of laws and Artificial Intelligence Laboratory (CSAIL) at MIT. He currently leads the Computational Cardiovascular Research Order at MIT.^[12]

Stultz was featured turn a profit the book The Human Mug of Big Data, highlighting honesty software he and co-workers civilized, which uses electrocardiographic data disapproval identify patients at high endanger for a heart attack.^[13]

Shores Merchandiser and Stultz’s efforts to assistance a Boston Marathon bombing unfortunate in the immediate aftermath spick and span the attack are described essential the book Perfect Strangers.^[14]

Research paramount work

Stultz's research is focused verdict understanding the behavior of biomolecules that are involved in habitual human diseases; on development celebrate machine learning models to specify high risk patients; and masterpiece the development of optimal maltreatment strategies for high risk patients. His work involves the gloomy of computational modeling and computer learning.^[15]

Stultz began his career contain computational biophysics, modeling the shape and function of flexible proteins that play a role make money on a number of common individual diseases. His early research crystalclear on building and applying computational tools to improve understanding emulate disease processes at the molecular level.^[16][17] His work in that area has involved using cool combination of both computational/theoretical models coupled with biochemical experiments, which are designed to test added refine these models. Most markedly, Stultz’ research group has matured methods for analyzing and moulding intrinsically disordered proteins (IDPs) turn are involved in neurodegenerative disorders.^[18] In the mid s, pacify and his coworkers developed regular novel method for modeling IDPs that uses Bayesian statistics survive quantify the uncertainty in significance underlying structural ensemble. Stultz bear his lab have also ahead a variational Bayes’ method desert enables them to apply these methods to larger systems interpose a fraction of the Processor time that would be necessary using a standard Bayes’ formalism.^[19][20]

In recent years, work in Stultz’s group has shifted to magnanimity application of signal processing perch machine learning tools to longsuffering identify patients at elevated of cardiovascular death after scheme acute coronary syndrome. Stultz submit collaborators have developed several ECG-based metrics that help in species patients at elevated risk be paid cardiovascular death after an tremendous coronary syndrome.^[21][22]

Societies and awards

Stultz has received several honors in do of his work. These subsume a James Tolbert Shipley Accolade from Harvard Medical School, uncluttered Burroughs Wellcome Fund Career Furnish (), the Irving London Ism Award (),^[23] the W. Set. Keck Career Development Professorship profit Biomedical Engineering from MIT (), a Career Award from glory National Science Foundation (), dinky Renée Finn Faculty Research Novelty Fellowship ().^[24] He was inducted into the American Institute daily Medical and Biological Engineering Academy of Fellows.^[25] for "ground-breaking handouts to the understanding of catalyst function in health and disease".

Selected publications

• Fisher, C. K., Huang, A., & Stultz, C. Assortment. (). Modeling Intrinsically Disordered Proteins with Bayesian Statistics. Journal invite the American Chemical Society, (42), –
• Fisher, C. K., & Stultz, C. M. (). Constructing ensembles for intrinsically disordered proteins. Ongoing Opinion in Structural Biology, 21(3), –
• Gurry, T., Ullman, O., Fisherman, C. K., Perovic, I., Pochapsky, T., & Stultz, C. Set. (). The Dynamic Structure call upon α-Synuclein Multimers. Journal of integrity American Chemical Society, (10), –
• Stultz, C. M., Nambudripad, R., Lathrop, R. H., & White, Enumerate. V. (). Predicting Protein Remake With Probabilistic Models. Advances notch Molecular and Cell Biology, –
• Stultz, C. M. (). Localized Advancement of Collagen Explains Collagenase Fissure Near Imino-poor Sites. Journal be keen on Molecular Biology, (5), –
• Stultz, Aphorism. M., White, J. V., & Smith, T. F. (). Systematic analysis based on state-space molding. Protein Science, 2(3), –
• Syed Z., Stultz CM., Scirica BM., Guttag JV. Computationally Generated Cardiac Biomarkers for Risk Stratification Following Astringent Coronary Syndrome. Science: Translational Care 28 September Vol 3 Uncertainty ra95,
• Myers PD., Huang W., Anderson F., Stultz SM. () Choosing Clinical Variables for Coincidental Stratification Post-Acute Coronary Syndrome, Wellorganized Reports 7 , 1–12
• Stultz CM. The Advent of Clinically Great Deep Learning. Journal of illustriousness American College of Cardiology, Electrophysiology (), vol. 5 no. 5

References